5Y7H
Crystal structure of human DPP4 in complex with inhibitor3
Summary for 5Y7H
Entry DOI | 10.2210/pdb5y7h/pdb |
Descriptor | Dipeptidyl peptidase 4, (R)-4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)piperazin-2-one (3 entities in total) |
Functional Keywords | dpp4, inhibitor, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 170186.40 |
Authors | |
Primary citation | Lee, H.K.,Kim, M.K.,Kim, H.D.,Kim, H.J.,Kim, J.W.,Lee, J.O.,Kim, C.W.,Kim, E.E. Unique binding mode of Evogliptin with human dipeptidyl peptidase IV. Biochem.Biophys.Res.Commun., 494:452-459, 2017 Cited by PubMed: 29061303DOI: 10.1016/j.bbrc.2017.10.101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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