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5Y7H

Crystal structure of human DPP4 in complex with inhibitor3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Dipeptidyl peptidase 4polymer72884462.62UniProt (P27487)
Pfam (PF00930)
Pfam (PF00326)
Homo sapiens (Human)ADABP,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,DPP IV,T-cell activation antigen CD26,TP103
2C, D, E, F
(A, B)
(R)-4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)piperazin-2-onenon-polymer315.34Chemie (8O3)
3G, H
(A, B)
waterwater18.0150Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight168925.2
Non-Polymers*Number of molecules4
Total formula weight1261.2
All*Total formula weight170186.4
*Water molecules are not included.

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PDB entries from 2026-01-28

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