Crystal structure of human Spindlin1 in complex with a histone H4K20(me3) peptide

Summary for 5Y5W

DescriptorSpindlin-1, Histone peptide H4K20(me3) (2 entities in total)
Functional Keywordsreader, histone, gene regulation
Biological sourceHomo sapiens (Human)
Total number of polymer chains7
Total molecular weight111181.88
Wang, C.,Zang, J. (deposition date: 2017-08-10, release date: 2017-10-11, Last modification date: 2019-03-27)
Primary citation
Wang, C.,Zhan, L.,Wu, M.,Ma, R.,Yao, J.,Xiong, Y.,Pan, Y.,Guan, S.,Zhang, X.,Zang, J.
Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail
FEBS Lett., 592:4098-4110, 2018
PubMed: 30381828 (PDB entries with the same primary citation)
DOI: 10.1002/1873-3468.13281
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.31450 7.2% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5y5w
no rotation
Molmil generated image of 5y5w
rotated about x axis by 90°
Molmil generated image of 5y5w
rotated about y axis by 90°