5Y3K

Crystal structure of horse TLR9 in complex with two DNAs (CpG DNA and GCGCAC DNA)

5Y3K の概要

• エントリーDOI: 10.2210/pdb5y3k/pdb
• 分子名称: Toll-like receptor 9, DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*GP*CP*GP*CP*AP*C)-3'), ... (6 entities in total)
• 機能のキーワード: innate immunity, toll-like receptor, leucine-rich repeat, dna binding, immune system
• 由来する生物種: Equus caballus (Horse); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 192742.48

構造登録者

Ohto, U.,Shimizu, T. (登録日: 2017-07-29, 公開日: 2018-04-18, 最終更新日: 2023-11-22)

• 主引用文献: Ohto, U.,Ishida, H.,Shibata, T.,Sato, R.,Miyake, K.,Shimizu, T.; Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation; Immunity, 48:649-658.e4, 2018; PubMed: 29625894; DOI: 10.1016/j.immuni.2018.03.013

実験手法

X-RAY DIFFRACTION (2.7 Å)