5XWR

Crystal Structure of RBBP4-peptide complex

Summary for 5XWR

Entry DOI	10.2210/pdb5xwr/pdb
Descriptor	Histone-binding protein RBBP4, MET-SER-ARG-ARG-LYS-GLN-ALA-LYS-PRO-GLN-HIS-ILE (3 entities in total)
Functional Keywords	histone binding protein, sall4, transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	102919.60
Authors	Jobichen, C.,Lui, B.H.,Daniel, G.T.,Sivaraman, J. (deposition date: 2017-06-30, release date: 2018-07-11, Last modification date: 2023-11-22)
Primary citation	Liu, B.H.,Jobichen, C.,Chia, C.S.B.,Chan, T.H.M.,Tang, J.P.,Chung, T.X.Y.,Li, J.,Poulsen, A.,Hung, A.W.,Koh-Stenta, X.,Tan, Y.S.,Verma, C.S.,Tan, H.K.,Wu, C.S.,Li, F.,Hill, J.,Joy, J.,Yang, H.,Chai, L.,Sivaraman, J.,Tenen, D.G. Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide. Proc. Natl. Acad. Sci. U.S.A., 115:E7119-E7128, 2018 Cited by PubMed: 29976840 DOI: 10.1073/pnas.1801253115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.69 Å)

Structure validation