5XS8

Crystal structure of solute-binding protein complexed with unsaturated chondroitin disaccharide with two sulfate groups at C-4 and C-6 positions of GalNAc

Summary for 5XS8

Entry DOI	10.2210/pdb5xs8/pdb
Descriptor	Extracellular solute-binding protein family 1, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4,6-di-O-sulfo-beta-D-galactopyranose, CALCIUM ION, ... (4 entities in total)
Functional Keywords	glycosaminoglycan, abc transporter, solute-binding protein, sugar binding protein
Biological source	Streptobacillus moniliformis DSM 12112
Total number of polymer chains	4
Total formula weight	232446.98
Authors	Oiki, S.,Kamochi, R.,Mikami, B.,Murata, K.,Hashimoto, W. (deposition date: 2017-06-12, release date: 2018-01-17, Last modification date: 2023-11-22)
Primary citation	Oiki, S.,Kamochi, R.,Mikami, B.,Murata, K.,Hashimoto, W. Alternative substrate-bound conformation of bacterial solute-binding protein involved in the import of mammalian host glycosaminoglycans. Sci Rep, 7:17005-17005, 2017 Cited by PubMed: 29208901 DOI: 10.1038/s41598-017-16801-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.952 Å)

Structure validation