5XP9

Crystal structure of Bismuth bound NDM-1

Summary for 5XP9

• Entry DOI: 10.2210/pdb5xp9/pdb
• Descriptor: Metallo-beta-lactamase type 2, Bismuth(III) ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: antibiotics resistance, beta-lactamase, metallodrug, bismuth, hydrolase
• Biological source: Klebsiella pneumoniae
• Cellular location: Periplasm : C7C422
• Total number of polymer chains: 1
• Total formula weight: 26019.97

Authors

Zhang, H.,Ma, G.,Lai, T.P.,Sun, H. (deposition date: 2017-06-01, release date: 2018-03-07, Last modification date: 2023-11-22)

• Primary citation: Wang, R.,Lai, T.P.,Gao, P.,Zhang, H.,Ho, P.L.,Woo, P.C.,Ma, G.,Kao, R.Y.,Li, H.,Sun, H.; Bismuth antimicrobial drugs serve as broad-spectrum metallo-beta-lactamase inhibitors; Nat Commun, 9:439-439, 2018; PubMed: 29382822; DOI: 10.1038/s41467-018-02828-6

Experimental method

X-RAY DIFFRACTION (1.55 Å)