5XP1

Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 6

Replaces:  5B3C

Summary for 5XP1

• Entry DOI: 10.2210/pdb5xp1/pdb
• Descriptor: Immunoglobulin kappa variable 1D-33 (2 entities in total)
• Functional Keywords: immunoglobulin, immune system
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted : P01593
• Total number of polymer chains: 8
• Total formula weight: 95570.13

Authors

Mine, S.,Nakamura, T.,Uegaki, K.,Hamada, D. (deposition date: 2017-05-31, release date: 2017-08-02, Last modification date: 2023-11-22)

• Primary citation: Nawata, M.,Tsutsumi, H.,Kobayashi, Y.,Unzai, S.,Mine, S.,Nakamura, T.,Uegaki, K.,Kamikubo, H.,Kataoka, M.,Hamada, D.; Heat-induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light-chain REI; FEBS J., 284:3114-3127, 2017; PubMed: 28736891; DOI: 10.1111/febs.14181

Experimental method

X-RAY DIFFRACTION (2.88 Å)