5XO2

Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide II

Summary for 5XO2

• Entry DOI: 10.2210/pdb5xo2/pdb
• Descriptor: Paired immunoglobulin-like type 2 receptor alpha, Peptide from Envelope glycoprotein B, N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2,4-dideoxy-alpha-D-xylo-hexopyranose, ... (4 entities in total)
• Functional Keywords: membrane protein, immune receptor, viral entry inhibitor, glycopeptide, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Cell membrane ; Single-pass type I membrane protein . Isoform 3: Secreted . Isoform 4: Secreted : Q9UKJ1; Virion membrane ; Single-pass type I membrane protein : P06437
• Total number of polymer chains: 4
• Total formula weight: 30147.66

Authors

Furukawa, A.,Kakita, K.,Yamada, T.,Ishizuka, M.,Sakamoto, J.,Hatori, N.,Maeda, N.,Ohsaka, F.,Saitoh, T.,Nomura, T.,Kuroki, K.,Nambu, H.,Arase, H.,Matsunaga, S.,Anada, M.,Ose, T.,Hashimoto, S.,Maenaka, K. (deposition date: 2017-05-25, release date: 2017-10-25, Last modification date: 2023-11-22)

• Primary citation: Furukawa, A.,Kakita, K.,Yamada, T.,Ishizuka, M.,Sakamoto, J.,Hatori, N.,Maeda, N.,Ohsaka, F.,Saitoh, T.,Nomura, T.,Kuroki, K.,Nambu, H.,Arase, H.,Matsunaga, S.,Anada, M.,Ose, T.,Hashimoto, S.,Maenaka, K.; Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor.; J. Biol. Chem., 292:21128-21136, 2017; PubMed: 29046357; DOI: 10.1074/jbc.M117.799239

Experimental method

X-RAY DIFFRACTION (2.201 Å)