5XHG
Crystal structure of Trastuzumab Fab fragment bearing Ne-(o-azidobenzyloxycarbonyl)-L-lysine
Summary for 5XHG
Entry DOI | 10.2210/pdb5xhg/pdb |
Descriptor | polypeptide(L), polypeptide(H), (2-azidophenyl)methyl hydrogen carbonate, ... (7 entities in total) |
Functional Keywords | fab, immune system |
Biological source | MUS MUSCULUS (MOUSE) More |
Total number of polymer chains | 4 |
Total formula weight | 95036.72 |
Authors | Kuratani, M.,Yanagisawa, T.,Sakamoto, K.,Yokoyama, S. (deposition date: 2017-04-20, release date: 2017-12-20, Last modification date: 2019-12-25) |
Primary citation | Kato, A.,Kuratani, M.,Yanagisawa, T.,Ohtake, K.,Hayashi, A.,Amano, Y.,Kimura, K.,Yokoyama, S.,Sakamoto, K.,Shiraishi, Y. Extensive Survey of Antibody Invariant Positions for Efficient Chemical Conjugation Using Expanded Genetic Codes. Bioconjug. Chem., 28:2099-2108, 2017 Cited by PubMed: 28727448DOI: 10.1021/acs.bioconjchem.7b00265 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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