5XB3

ADP-dTMP bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

Summary for 5XB3

Entry DOI	10.2210/pdb5xb3/pdb
Related	5XAI 5XB2 5XB5 5XBH
Descriptor	Thymidylate kinase, ADENOSINE-5'-DIPHOSPHATE, THYMIDINE-5'-PHOSPHATE, ... (4 entities in total)
Functional Keywords	kinase, complex, nucleotide binding, transferase
Biological source	Aquifex aeolicus (strain VF5)
Total number of polymer chains	2
Total formula weight	46304.74
Authors	Biswas, A.,Jeyakanthan, J.,Sekar, K. (deposition date: 2017-03-15, release date: 2017-06-28, Last modification date: 2023-11-22)
Primary citation	Biswas, A.,Shukla, A.,Chaudhary, S.K.,Santhosh, R.,Jeyakanthan, J.,Sekar, K. Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate FEBS J., 284:2527-2544, 2017 Cited by PubMed: 28627020 DOI: 10.1111/febs.14140 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation