5XB3
ADP-dTMP bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5
Summary for 5XB3
Entry DOI | 10.2210/pdb5xb3/pdb |
Related | 5XAI 5XB2 5XB5 5XBH |
Descriptor | Thymidylate kinase, ADENOSINE-5'-DIPHOSPHATE, THYMIDINE-5'-PHOSPHATE, ... (4 entities in total) |
Functional Keywords | kinase, complex, nucleotide binding, transferase |
Biological source | Aquifex aeolicus (strain VF5) |
Total number of polymer chains | 2 |
Total formula weight | 46304.74 |
Authors | Biswas, A.,Jeyakanthan, J.,Sekar, K. (deposition date: 2017-03-15, release date: 2017-06-28, Last modification date: 2023-11-22) |
Primary citation | Biswas, A.,Shukla, A.,Chaudhary, S.K.,Santhosh, R.,Jeyakanthan, J.,Sekar, K. Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate FEBS J., 284:2527-2544, 2017 Cited by PubMed: 28627020DOI: 10.1111/febs.14140 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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