5WYM
Crystal structure of an anti-connexin26 scFv
Summary for 5WYM
Entry DOI | 10.2210/pdb5wym/pdb |
Descriptor | anti-connexin26 scFv,Ig heavy chain,Linker,anti-connexin26 scFv,Ig light chain (2 entities in total) |
Functional Keywords | antibody, scfv, connexin26, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 50928.68 |
Authors | |
Primary citation | Xu, L.,Carrer, A.,Zonta, F.,Qu, Z.,Ma, P.,Li, S.,Ceriani, F.,Buratto, D.,Crispino, G.,Zorzi, V.,Ziraldo, G.,Bruno, F.,Nardin, C.,Peres, C.,Mazzarda, F.,Salvatore, A.M.,Raspa, M.,Scavizzi, F.,Chu, Y.,Xie, S.,Yang, X.,Liao, J.,Liu, X.,Wang, W.,Wang, S.,Yang, G.,Lerner, R.A.,Mammano, F. Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders Front Mol Neurosci, 10:298-298, 2017 Cited by PubMed: 29018324DOI: 10.3389/fnmol.2017.00298 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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