5WYM

Crystal structure of an anti-connexin26 scFv

5WYM の概要

• エントリーDOI: 10.2210/pdb5wym/pdb
• 分子名称: anti-connexin26 scFv,Ig heavy chain,Linker,anti-connexin26 scFv,Ig light chain (2 entities in total)
• 機能のキーワード: antibody, scfv, connexin26, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 50928.68

構造登録者

Li, S.,Xu, L. (登録日: 2017-01-13, 公開日: 2018-01-24, 最終更新日: 2023-11-22)

• 主引用文献: Xu, L.,Carrer, A.,Zonta, F.,Qu, Z.,Ma, P.,Li, S.,Ceriani, F.,Buratto, D.,Crispino, G.,Zorzi, V.,Ziraldo, G.,Bruno, F.,Nardin, C.,Peres, C.,Mazzarda, F.,Salvatore, A.M.,Raspa, M.,Scavizzi, F.,Chu, Y.,Xie, S.,Yang, X.,Liao, J.,Liu, X.,Wang, W.,Wang, S.,Yang, G.,Lerner, R.A.,Mammano, F.; Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders; Front Mol Neurosci, 10:298-298, 2017; PubMed: 29018324; DOI: 10.3389/fnmol.2017.00298

実験手法

X-RAY DIFFRACTION (2.65 Å)