5WS8
Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate
Summary for 5WS8
Entry DOI | 10.2210/pdb5ws8/pdb |
Related | 5WRP 5WS9 5WSA 5WSB 5WSC |
Descriptor | Pyruvate kinase, MAGNESIUM ION, OXALATE ION, ... (4 entities in total) |
Functional Keywords | pyruvate kinase, glycolysis, tetramer, allostery, synergism, phospho transferase, transferase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 4 |
Total formula weight | 204506.64 |
Authors | Zhong, W.,Cai, Q.,El Sahili, A.,Lescar, J.,Dedon, P.C. (deposition date: 2016-12-06, release date: 2017-11-15, Last modification date: 2023-11-08) |
Primary citation | Zhong, W.,Cui, L.,Goh, B.C.,Cai, Q.,Ho, P.,Chionh, Y.H.,Yuan, M.,Sahili, A.E.,Fothergill-Gilmore, L.A.,Walkinshaw, M.D.,Lescar, J.,Dedon, P.C. Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis. Nat Commun, 8:1986-1986, 2017 Cited by PubMed: 29215013DOI: 10.1038/s41467-017-02086-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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