5WR0
Huisgen cycloaddition for PPARg-LBD labeling by soaking method
Summary for 5WR0
| Entry DOI | 10.2210/pdb5wr0/pdb |
| Descriptor | Peroxisome proliferator-activated receptor gamma, (E)-N-[(3E)-2-oxo-16-(8-{6-[(trifluoroacetyl)amino]hexanoyl}-8,9-dihydro-1H-dibenzo[b,f][1,2,3]triazolo[4,5-d]azocin-1-yl)hexadec-3-en-1-ylidene]glycine (3 entities in total) |
| Functional Keywords | receptor, transcription |
| Biological source | Homo sapiens (Human) |
| Cellular location | Nucleus: P37231 |
| Total number of polymer chains | 2 |
| Total formula weight | 63663.92 |
| Authors | Kojima, H.,Itoh, T.,Yamamoto, K. (deposition date: 2016-11-29, release date: 2017-11-22, Last modification date: 2017-12-13) |
| Primary citation | Kojima, H.,Itoh, T.,Yamamoto, K. On-site reaction for PPAR gamma modification using a specific bifunctional ligand Bioorg. Med. Chem., 25:6492-6500, 2017 Cited by PubMed: 29097031DOI: 10.1016/j.bmc.2017.10.024 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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