5WQT
Structure of a protein involved in pyroptosis
Summary for 5WQT
Entry DOI | 10.2210/pdb5wqt/pdb |
Descriptor | Gasdermin-D, GLYCEROL, CITRIC ACID, ... (4 entities in total) |
Functional Keywords | pyrtosis, signaling protein |
Biological source | Homo sapiens (Human) |
Cellular location | Gasdermin-D: Cytoplasm, cytosol . Gasdermin-D, N-terminal: Cell membrane : P57764 |
Total number of polymer chains | 2 |
Total formula weight | 45684.52 |
Authors | |
Primary citation | Kuang, S.,Zheng, J.,Yang, H.,Li, S.,Duan, S.,Shen, Y.,Ji, C.,Gan, J.,Xu, X.W.,Li, J. Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis. Proc. Natl. Acad. Sci. U.S.A., 114:10642-10647, 2017 Cited by PubMed: 28928145DOI: 10.1073/pnas.1708194114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.64 Å) |
Structure validation
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