5WP6
Cryo-EM structure of a human TRPM4 channel in complex with calcium and decavanadate
Summary for 5WP6
Entry DOI | 10.2210/pdb5wp6/pdb |
EMDB information | 8871 8872 8875 8876 8877 8878 8879 |
Descriptor | Transient receptor potential cation channel subfamily M member 4, DECAVANADATE (2 entities in total) |
Functional Keywords | ion channel, membrane protein |
Biological source | Homo sapiens (Human) |
Cellular location | Isoform 1: Cell membrane; Multi-pass membrane protein. Isoform 2: Endoplasmic reticulum: Q8TD43 |
Total number of polymer chains | 4 |
Total formula weight | 545485.12 |
Authors | Winkler, P.A.,Huang, Y.,Sun, W.,Du, J.,Lu, W. (deposition date: 2017-08-03, release date: 2017-12-13, Last modification date: 2024-05-15) |
Primary citation | Winkler, P.A.,Huang, Y.,Sun, W.,Du, J.,Lu, W. Electron cryo-microscopy structure of a human TRPM4 channel. Nature, 552:200-204, 2017 Cited by PubMed: 29211723DOI: 10.1038/nature24674 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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