5WNO

Crystal structure of C. elegans LET-23 kinase domain complexed with AMP-PNP

5WNO の概要

• エントリーDOI: 10.2210/pdb5wno/pdb
• 分子名称: Receptor tyrosine-protein kinase let-23, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: receptor tyrosine-protein kinase, dimerization, inactive conformation, cell signaling, let-23, c. elegans, transferase
• 由来する生物種: Caenorhabditis elegans
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38480.11

構造登録者

Liu, L.,Thaker, T.M.,Jura, N. (登録日: 2017-08-01, 公開日: 2018-01-31, 最終更新日: 2023-10-04)

• 主引用文献: Liu, L.,Thaker, T.M.,Freed, D.M.,Frazier, N.,Malhotra, K.,Lemmon, M.A.,Jura, N.; Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23.; Structure, 26:270-281.e4, 2018; PubMed: 29358026; DOI: 10.1016/j.str.2017.12.012

実験手法

X-RAY DIFFRACTION (2.386 Å)