5WNJ
Crystal structure of murine receptor-interacting protein kinase 4 (Ripk4) D143N in complex with lestaurtinib
Summary for 5WNJ
| Entry DOI | 10.2210/pdb5wnj/pdb |
| Related | 5WNI 5WNK 5WNL 5WNM |
| Descriptor | Receptor-interacting serine/threonine-protein kinase 4, Lestaurtinib, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | kinase, inhibitor, complex, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Mus musculus (Mouse) |
| Cellular location | Cytoplasm: Q9ERK0 |
| Total number of polymer chains | 1 |
| Total formula weight | 39462.96 |
| Authors | Huang, C.S.,Hymowitz, S.G. (deposition date: 2017-08-01, release date: 2018-05-09, Last modification date: 2024-05-22) |
| Primary citation | Huang, C.S.,Oberbeck, N.,Hsiao, Y.C.,Liu, P.,Johnson, A.R.,Dixit, V.M.,Hymowitz, S.G. Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure, 26:767-, 2018 Cited by PubMed: 29706531DOI: 10.1016/j.str.2018.04.002 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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