5WMX

Structural Insights into Substrate and Inhibitor Binding Sites in Human Indoleamine 2,3-Dioxygenase 1

Summary for 5WMX

Entry DOI	10.2210/pdb5wmx/pdb
Related	5WMU 5WMV 5WMW
Descriptor	Indoleamine 2,3-dioxygenase 1, CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
Functional Keywords	dioxygenase tryptophan heme inhibitor, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	97419.45
Authors	Lewis-Ballester, A.,Yeh, S.R.,Pham, K.N.,Batabyal, D.,Karkashon, S.,Bonanno, J.B.,Poulos, T.M. (deposition date: 2017-07-31, release date: 2017-12-06, Last modification date: 2023-10-04)
Primary citation	Lewis-Ballester, A.,Pham, K.N.,Batabyal, D.,Karkashon, S.,Bonanno, J.B.,Poulos, T.L.,Yeh, S.R. Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1. Nat Commun, 8:1693-1693, 2017 Cited by PubMed: 29167421 DOI: 10.1038/s41467-017-01725-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.69 Å)

Structure validation