5WM1

Structure of the 10S (+)-trans-BP-dG modified Rev1 ternary complex

5WM1 の概要

• エントリーDOI: 10.2210/pdb5wm1/pdb
• 分子名称: DNA (5'-D(*GP*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*(DDG))-3'), DNA (5'-D(P*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), DNA repair protein REV1, ... (10 entities in total)
• 機能のキーワード: benzo[a]pyrene rev1 polymerase carcinogen lesion bypass, dna binding protein, transferase-dna complex, transferase/dna
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 60220.57

構造登録者

Rechkoblit, O.,Kolbanovsky, A.,Landes, H.,Geacintov, N.E.,Aggarwal, A.K. (登録日: 2017-07-28, 公開日: 2017-10-25, 最終更新日: 2023-10-04)

• 主引用文献: Rechkoblit, O.,Kolbanovskiy, A.,Landes, H.,Geacintov, N.E.,Aggarwal, A.K.; Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.; Nat Commun, 8:965-965, 2017; PubMed: 29042535; DOI: 10.1038/s41467-017-01013-5

実験手法

X-RAY DIFFRACTION (1.85 Å)