5WIB
Structure of Acinetobacter baumannii carbapenemase OXA-239 K82D bound to imipenem
Summary for 5WIB
| Entry DOI | 10.2210/pdb5wib/pdb |
| Descriptor | OXA-239, Imipenem (3 entities in total) |
| Functional Keywords | beta-lactamase, antibiotic resistance, hydrolase |
| Biological source | Acinetobacter sp. enrichment culture clone 8407 |
| Total number of polymer chains | 2 |
| Total formula weight | 58175.06 |
| Authors | Harper, T.M.,June, C.M.,Powers, R.A.,Leonard, D.A. (deposition date: 2017-07-19, release date: 2017-12-27, Last modification date: 2023-10-04) |
| Primary citation | Harper, T.M.,June, C.M.,Taracila, M.A.,Bonomo, R.A.,Powers, R.A.,Leonard, D.A. Multiple substitutions lead to increased loop flexibility and expanded specificity in Acinetobacter baumannii carbapenemase OXA-239. Biochem. J., 475:273-288, 2018 Cited by PubMed: 29229762DOI: 10.1042/BCJ20170702 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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