5WCJ
Crystal Structure of Human Methyltransferase-like protein 13 in complex with SAH
Summary for 5WCJ
Entry DOI | 10.2210/pdb5wcj/pdb |
Descriptor | Methyltransferase-like protein 13, UNKNOWN ATOM OR ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total) |
Functional Keywords | methyltransferase, rossman fold, sah-binding, sgc, structural genomics, structural genomics consortium, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 27924.41 |
Authors | Halabelian, L.,Loppnau, P.,Seitova, A.,Hutchinson, A.,Hunt, B.,Dong, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Structural Genomics Consortium (SGC) (deposition date: 2017-06-30, release date: 2017-07-19, Last modification date: 2023-10-04) |
Primary citation | Jakobsson, M.E.,Malecki, J.M.,Halabelian, L.,Nilges, B.S.,Pinto, R.,Kudithipudi, S.,Munk, S.,Davydova, E.,Zuhairi, F.R.,Arrowsmith, C.H.,Jeltsch, A.,Leidel, S.A.,Olsen, J.V.,Falnes, P.O. The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates. Nat Commun, 9:3411-3411, 2018 Cited by PubMed: 30143613DOI: 10.1038/s41467-018-05646-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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