5WCG

SET and MYND Domain Containing protein 2

Summary for 5WCG

• Entry DOI: 10.2210/pdb5wcg/pdb
• Descriptor: N-lysine methyltransferase SMYD2, ZINC ION, [3-(6-amino-2-methyl-9H-purin-9-yl)azetidin-1-yl]{5-[(4-cycloheptylpiperazin-1-yl)methyl]-1-methyl-1H-pyrazol-3-yl}methanone, ... (7 entities in total)
• Functional Keywords: zinc finger, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm, cytosol : Q9NRG4
• Total number of polymer chains: 1
• Total formula weight: 50735.31

Authors

Dong, A.,Zeng, H.,Walker, J.R.,Hutch, A.,Seitova, A.,Tatlock, J.,Kumpf, R.,Owen, A.,Taylor, A.,Casimiro-Garcia, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2017-06-30, release date: 2017-08-02, Last modification date: 2023-10-04)

• Primary citation: Zeng, H.,Dong, A.,Walker, J.R.,Hutch, A.,Seitova, A.,Tatlock, J.,Kumpf, R.,Owen, A.,Taylor, A.,Casimiro-Garcia, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Wu, H.; The crystal structure of SMYD2 in complex with compound MTF003; to be published,

Experimental method

X-RAY DIFFRACTION (2.02 Å)