5WB9
Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E strain 93TH057 gp120 core
Summary for 5WB9
Entry DOI | 10.2210/pdb5wb9/pdb |
Descriptor | clade A/E 93TH057 HIV-1 gp120 core, N60P23 Fab heavy chain, N60P23 Fab light chain, ... (7 entities in total) |
Functional Keywords | cd4 binding site, gp120 core, viral protein |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 88842.67 |
Authors | Gohain, N.,Tolbert, W.,Pazgier, M. (deposition date: 2017-06-28, release date: 2018-05-23, Last modification date: 2023-10-04) |
Primary citation | Sajadi, M.M.,Dashti, A.,Rikhtegaran Tehrani, Z.,Tolbert, W.D.,Seaman, M.S.,Ouyang, X.,Gohain, N.,Pazgier, M.,Kim, D.,Cavet, G.,Yared, J.,Redfield, R.R.,Lewis, G.K.,DeVico, A.L. Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses. Cell, 173:1783-1795.e14, 2018 Cited by PubMed: 29731169DOI: 10.1016/j.cell.2018.03.061 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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