5WB9

Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E strain 93TH057 gp120 core

Summary for 5WB9

Entry DOI	10.2210/pdb5wb9/pdb
Descriptor	clade A/E 93TH057 HIV-1 gp120 core, N60P23 Fab heavy chain, N60P23 Fab light chain, ... (7 entities in total)
Functional Keywords	cd4 binding site, gp120 core, viral protein
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	3
Total formula weight	88842.67
Authors	Gohain, N.,Tolbert, W.,Pazgier, M. (deposition date: 2017-06-28, release date: 2018-05-23, Last modification date: 2023-10-04)
Primary citation	Sajadi, M.M.,Dashti, A.,Rikhtegaran Tehrani, Z.,Tolbert, W.D.,Seaman, M.S.,Ouyang, X.,Gohain, N.,Pazgier, M.,Kim, D.,Cavet, G.,Yared, J.,Redfield, R.R.,Lewis, G.K.,DeVico, A.L. Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses. Cell, 173:1783-1795.e14, 2018 Cited by PubMed: 29731169 DOI: 10.1016/j.cell.2018.03.061 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation