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5WA3

Pyridine synthase, TbtD, from thiomuracin biosynthesis

Summary for 5WA3
Entry DOI10.2210/pdb5wa3/pdb
DescriptorPyridine synthase TbtD (1 entity in total)
Functional Keywordspyridine synthase, diels-alder, thiopeptide, thiomuracin, biosynthetic protein
Biological sourceThermobispora bispora
Total number of polymer chains2
Total formula weight80641.11
Authors
Cogan, D.P.,Nair, S.K. (deposition date: 2017-06-24, release date: 2017-11-22, Last modification date: 2023-10-04)
Primary citationCogan, D.P.,Hudson, G.A.,Zhang, Z.,Pogorelov, T.V.,van der Donk, W.A.,Mitchell, D.A.,Nair, S.K.
Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis.
Proc. Natl. Acad. Sci. U.S.A., 114:12928-12933, 2017
Cited by
PubMed: 29158402
DOI: 10.1073/pnas.1716035114
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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