5WA1
CHMP4C A232T in complex with ALIX BRO1
Summary for 5WA1
Entry DOI | 10.2210/pdb5wa1/pdb |
Related | 3C3R |
Descriptor | Programmed cell death 6-interacting protein, Charged multivesicular body protein 4c (3 entities in total) |
Functional Keywords | cell division, transport protein, abscission checkpoint, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 44757.88 |
Authors | Wenzel, D.M.,Alam, S.L.,Sundquist, W.I. (deposition date: 2017-06-24, release date: 2018-09-19, Last modification date: 2023-10-04) |
Primary citation | Sadler, J.B.A.,Wenzel, D.M.,Williams, L.K.,Guindo-Martinez, M.,Alam, S.L.,Mercader, J.M.,Torrents, D.,Ullman, K.S.,Sundquist, W.I.,Martin-Serrano, J. A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability. Proc. Natl. Acad. Sci. U.S.A., 115:E8900-E8908, 2018 Cited by PubMed: 30181294DOI: 10.1073/pnas.1805504115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.868 Å) |
Structure validation
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