5W8R
Toxoplasma Gondii CDPK1 in complex with inhibitor 3CIB-PPI
Summary for 5W8R
Entry DOI | 10.2210/pdb5w8r/pdb |
Descriptor | Calmodulin-domain protein kinase 1, 1-tert-butyl-3-[(3-chlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | cdpk, parasitology, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, transferase, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Toxoplasma gondii |
Total number of polymer chains | 1 |
Total formula weight | 55582.79 |
Authors | El Bakkouri, M.,Lovato, D.,Loppnau, P.,Lin, Y.H.,Rutaganaria, F.,Lopez, M.S.,Shokat, L.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Sibley, D.,Hui, R.,Walker, J.R.,Structural Genomics Consortium (SGC) (deposition date: 2017-06-22, release date: 2017-07-19, Last modification date: 2023-10-04) |
Primary citation | El Bakkouri, M.,Lovato, D.,Loppnau, P.,Lin, Y.H.,Rutaganaria, F.,Lopez, M.S.,Shokat, L.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Sibley, D.,Hui, R.,Walker, J.R.,Structural Genomics Consortium (SGC) Toxoplasma Gondii CDPK1 in complex with inhibitor 3CIB-PPI To be published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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