5W80

Toxoplasma Gondii CDPK1 in complex with inhibitor GXJ-237

Summary for 5W80

Entry DOI	10.2210/pdb5w80/pdb
Descriptor	Calmodulin-domain protein kinase 1, 3-(3-chlorophenoxy)-1-[(piperidin-4-yl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, ... (4 entities in total)
Functional Keywords	cdpk, parasitology, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, transferase, structural genomics, structural genomics consortium, sgc
Biological source	Toxoplasma gondii
Total number of polymer chains	1
Total formula weight	55625.82
Authors	El Bakkouri, M.,Lovato, D.,Loppnau, P.,Lin, Y.H.,Rutaganaria, F.,Lopez, M.S.,Shokat, L.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Sibley, D.,Walker, J.R.,Structural Genomics Consortium (SGC) (deposition date: 2017-06-21, release date: 2017-07-19, Last modification date: 2023-10-04)
Primary citation	El Bakkouri, M.,Lovato, D.,Loppnau, P.,Lin, Y.H.,Rutaganaria, F.,Lopez, M.S.,Shokat, L.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Sibley, D.,Hui, R.,Walker, J.R.,Structural Genomics Consortium (SGC) Toxoplasma Gondii CDPK1 in complex with inhibitor GXJ-237 To be published,
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation