5W6L

Crystal Structure of RRSP, a MARTX Toxin Effector Domain from Vibrio vulnificus CMCP6

5W6L の概要

• エントリーDOI: 10.2210/pdb5w6l/pdb
• 分子名称: RTX repeat-containing cytotoxin, GLYCEROL, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: structural genomics, center for structural genomics of infectious diseases, csgid, rrsp, martx toxin, effector domain, toxin
• 由来する生物種: Vibrio vulnificus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 116016.06

構造登録者

Minasov, G.,Wawrzak, Z.,Biancucci, M.,Shuvalova, L.,Dubrovska, I.,Satchell, K.J.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2017-06-16, 公開日: 2018-06-27, 最終更新日: 2018-10-10)

• 主引用文献: Biancucci, M.,Minasov, G.,Banerjee, A.,Herrera, A.,Woida, P.J.,Kieffer, M.B.,Bindu, L.,Abreu-Blanco, M.,Anderson, W.F.,Gaponenko, V.,Stephen, A.G.,Holderfield, M.,Satchell, K.J.F.; The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling.; Sci Signal, 11:-, 2018; PubMed: 30279169; DOI: 10.1126/scisignal.aat8335

実験手法

X-RAY DIFFRACTION (3.45 Å)