5W6D

Crystal structure of BG505-SOSIP.v4.1-GT1-N137A in complex with Fabs 35022 and 9H/109L

5W6D の概要

• エントリーDOI: 10.2210/pdb5w6d/pdb
• 分子名称: BG505-SOSIP.v4.1-GT1-N137A gp120, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• 機能のキーワード: hiv-1 broadly neutralizing antibody, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human immunodeficiency virus 1 (HIV-1); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 176226.50

構造登録者

Garces, F.,Stanfield, R.L.,Wilson, I.A. (登録日: 2017-06-16, 公開日: 2017-07-05, 最終更新日: 2023-10-04)

• 主引用文献: Medina-Ramirez, M.,Garces, F.,Escolano, A.,Skog, P.,de Taeye, S.W.,Del Moral-Sanchez, I.,McGuire, A.T.,Yasmeen, A.,Behrens, A.J.,Ozorowski, G.,van den Kerkhof, T.L.G.M.,Freund, N.T.,Dosenovic, P.,Hua, Y.,Gitlin, A.D.,Cupo, A.,van der Woude, P.,Golabek, M.,Sliepen, K.,Blane, T.,Kootstra, N.,van Breemen, M.J.,Pritchard, L.K.,Stanfield, R.L.,Crispin, M.,Ward, A.B.,Stamatatos, L.,Klasse, P.J.,Moore, J.P.,Nemazee, D.,Nussenzweig, M.C.,Wilson, I.A.,Sanders, R.W.; Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.; J. Exp. Med., 214:2573-2590, 2017; PubMed: 28847869; DOI: 10.1084/jem.20161160

実験手法

X-RAY DIFFRACTION (3.202 Å)