5W3S

Cryo-electron microscopy structure of a TRPML3 ion channel

Summary for 5W3S

Entry DOI	10.2210/pdb5w3s/pdb
Related	5W3S
EMDB information	8764
Descriptor	Mucolipin-3 isoform 1, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... (5 entities in total)
Functional Keywords	transient receptor potential channel, mucolipin, ion channel, membrane transport, trpml, trp channel, calcium channel, pip2, pi(3, 5)p2, lipid-gated channel, mucolipidosis, lysosomal ion channel, lysosome, transport protein
Biological source	Callithrix jacchus (White-tufted-ear marmoset)
Total number of polymer chains	4
Total formula weight	269340.12
Authors	Hirschi, M.,Herzik, M.A.,Wie, J.,Suo, Y.,Borschel, W.F.,Ren, D.,Lander, G.C.,Lee, S.Y. (deposition date: 2017-06-08, release date: 2017-10-11, Last modification date: 2024-03-13)
Primary citation	Hirschi, M.,Herzik, M.A.,Wie, J.,Suo, Y.,Borschel, W.F.,Ren, D.,Lander, G.C.,Lee, S.Y. Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3. Nature, 550:411-414, 2017 Cited by PubMed: 29019979 DOI: 10.1038/nature24055 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.94 Å)

Structure validation