5W2J

Crystal structure of dimeric form of mouse Glutaminase C

Summary for 5W2J

DescriptorGlutaminase kidney isoform, mitochondrial, unidentified peptide, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsglutamine metabolism, glutaminase, hydrolase
Biological sourceMus musculus (Mouse)
Total number of polymer chains3
Total molecular weight93045.01
Authors
Cerione, R.A.,Li, Y. (deposition date: 2017-06-06, release date: 2018-10-17, Last modification date: 2019-02-27)
Primary citation
Li, Y.,Erickson, J.W.,Stalnecker, C.A.,Katt, W.P.,Huang, Q.,Cerione, R.A.,Ramachandran, S.
Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS.
J. Biol. Chem., 291:20900-20910, 2016
PubMed: 27542409 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M116.720268
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24814 0.4% 9.6% 6.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5w2j
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Molmil generated image of 5w2j
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Molmil generated image of 5w2j
rotated about y axis by 90°