5W2A
Structure of human DNA polymerase kappa in complex with Lucidin-derived DNA adduct and incoming dCMPNPP
Summary for 5W2A
Entry DOI | 10.2210/pdb5w2a/pdb |
Related | 5W2C |
Descriptor | DNA polymerase kappa, DNA (5'-D(P*GP*CP*GP*GP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*AP*TP*GP*(LDG)P*CP*TP*GP*AP*TP*CP*CP*GP*C)-3'), ... (8 entities in total) |
Functional Keywords | translesion synthesis, lucidin-derived dna adduct, dna polymerase kappa, mutagenesis, replication |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9UBT6 |
Total number of polymer chains | 6 |
Total formula weight | 142281.22 |
Authors | |
Primary citation | Yockey, O.P.,Jha, V.,Ghodke, P.P.,Xu, T.,Xu, W.,Ling, H.,Pradeepkumar, P.I.,Zhao, L. Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase kappa. Chem. Res. Toxicol., 30:2023-2032, 2017 Cited by PubMed: 28972744DOI: 10.1021/acs.chemrestox.7b00227 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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