5W22
Crystal structure of human WT-KRAS in complex with GDP
Summary for 5W22
Entry DOI | 10.2210/pdb5w22/pdb |
Descriptor | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01116 |
Total number of polymer chains | 2 |
Total formula weight | 39722.70 |
Authors | Xu, S.,Long, B.,Boris, G.,Ni, S.,Kennedy, M.A. (deposition date: 2017-06-05, release date: 2017-12-06, Last modification date: 2024-03-13) |
Primary citation | Xu, S.,Long, B.N.,Boris, G.H.,Chen, A.,Ni, S.,Kennedy, M.A. Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras. Acta Crystallogr D Struct Biol, 73:970-984, 2017 Cited by PubMed: 29199977DOI: 10.1107/S2059798317015418 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.762 Å) |
Structure validation
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