5W1H
Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (24-nt spacer)
Summary for 5W1H
| Entry DOI | 10.2210/pdb5w1h/pdb |
| Related | 5W1I 5WLH |
| Descriptor | LbaCas13a (C2c2), mature crRNA, IODIDE ION, ... (5 entities in total) |
| Functional Keywords | nuclease rna binding protein, rna binding protein, rna binding protein-rna complex, rna binding protein/rna |
| Biological source | Lachnospiraceae bacterium More |
| Total number of polymer chains | 2 |
| Total formula weight | 189276.96 |
| Authors | Knott, G.J.,Doudna, J.A. (deposition date: 2017-06-03, release date: 2017-09-13, Last modification date: 2024-03-13) |
| Primary citation | Knott, G.J.,East-Seletsky, A.,Cofsky, J.C.,Holton, J.M.,Charles, E.,O'Connell, M.R.,Doudna, J.A. Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme. Nat. Struct. Mol. Biol., 24:825-833, 2017 Cited by PubMed: 28892041DOI: 10.1038/nsmb.3466 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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