5VYG

Crystal structure of hFA9 EGF repeat with O-glucose trisaccharide

5VYG の概要

• エントリーDOI: 10.2210/pdb5vyg/pdb
• 分子名称: Coagulation factor IX, alpha-D-xylopyranose-(1-3)-alpha-D-xylopyranose-(1-3)-beta-D-glucopyranose, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: notch regulation, egf repeat, glycosylation, transferase-hydrolase complex, transferase, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 18584.08

構造登録者

Yu, H.J.,Li, H.L. (登録日: 2017-05-25, 公開日: 2017-08-09, 最終更新日: 2023-10-04)

• 主引用文献: Takeuchi, H.,Yu, H.,Hao, H.,Takeuchi, M.,Ito, A.,Li, H.,Haltiwanger, R.S.; O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking; J. Biol. Chem., 292:15964-15973, 2017; PubMed: 28729422; DOI: 10.1074/jbc.M117.800102

実験手法

X-RAY DIFFRACTION (2.2 Å)