5VYF

Structure of single chain Fel d 1 bound to a neutralizing antibody

5VYF の概要

• エントリーDOI: 10.2210/pdb5vyf/pdb
• 分子名称: Antibody light chain, Antibody Fab heavy chain, Chimera of Major allergen I polypeptide chain 2,Major allergen I polypeptide chain 1, ... (5 entities in total)
• 機能のキーワード: antibody, allergen, therapeutic, immune system
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 137666.32

構造登録者

Franklin, M.C. (登録日: 2017-05-25, 公開日: 2018-04-04, 最終更新日: 2023-10-04)

• 主引用文献: Orengo, J.M.,Radin, A.R.,Kamat, V.,Badithe, A.,Ben, L.H.,Bennett, B.L.,Zhong, S.,Birchard, D.,Limnander, A.,Rafique, A.,Bautista, J.,Kostic, A.,Newell, D.,Duan, X.,Franklin, M.C.,Olson, W.,Huang, T.,Gandhi, N.A.,Lipsich, L.,Stahl, N.,Papadopoulos, N.J.,Murphy, A.J.,Yancopoulos, G.D.; Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.; Nat Commun, 9:1421-1421, 2018; PubMed: 29650949; DOI: 10.1038/s41467-018-03636-8

実験手法

X-RAY DIFFRACTION (2.9 Å)