5VY2

Crystal structure of the F36A mutant of HsNUDT16

Summary for 5VY2

• Entry DOI: 10.2210/pdb5vy2/pdb
• Related: 5W6X 5W6Z 5WJI 6B09
• Descriptor: U8 snoRNA-decapping enzyme, SODIUM ION (3 entities in total)
• Functional Keywords: nudix, nudix hydrolase, decapping enzyme, demodification of parylation, demodification of marylation, adpribose, di-adpribose, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 42531.65

Authors

Thirawatananond, P.,Gabelli, S.B. (deposition date: 2017-05-24, release date: 2018-11-21, Last modification date: 2024-04-03)

• Primary citation: Thirawatananond, P.,McPherson, R.L.,Malhi, J.,Nathan, S.,Lambrecht, M.J.,Brichacek, M.,Hergenrother, P.J.,Leung, A.K.L.,Gabelli, S.B.; Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.; Sci Rep, 9:5940-5940, 2019; PubMed: 30976021; DOI: 10.1038/s41598-019-39491-w

Experimental method

X-RAY DIFFRACTION (2.3 Å)