5VSJ

Sco GlgEI-V279S in complex with a pyrolidene-based ethyl-phosphonate compound

Summary for 5VSJ

Entry DOI	10.2210/pdb5vsj/pdb
Related	5VT4
Descriptor	Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, {2-[(2R,3R,4R,5R)-3-(alpha-D-glucopyranosyloxy)-4-hydroxy-2,5-bis(hydroxymethyl)pyrrolidin-1-yl]ethyl}phosphonic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	streptomyces coelicolor, maltosyltransferase, transition state analogue, alpha-1, 4-glucan, transferase
Biological source	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Total number of polymer chains	2
Total formula weight	149347.10
Authors	Petit, C.,Ronning, D.R. (deposition date: 2017-05-11, release date: 2017-05-31, Last modification date: 2023-10-04)
Primary citation	Veleti, S.K.,Petit, C.,Ronning, D.R.,Sucheck, S.J. Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S. Org. Biomol. Chem., 15:3884-3891, 2017 Cited by PubMed: 28422240 DOI: 10.1039/c7ob00388a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.456 Å)

Structure validation