5VP7
Crystal structure of human KRAS G12A mutant in complex with GDP
Summary for 5VP7
Entry DOI | 10.2210/pdb5vp7/pdb |
Related | 5VPI 5VPY 5VPZ 5VQ0 5VQ1 5VQ2 5VQ6 5VQ8 |
Descriptor | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | oncogenic mutant, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01116 |
Total number of polymer chains | 2 |
Total formula weight | 39946.90 |
Authors | |
Primary citation | Xu, S.,Long, B.N.,Boris, G.H.,Chen, A.,Ni, S.,Kennedy, M.A. Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras. Acta Crystallogr D Struct Biol, 73:970-984, 2017 Cited by PubMed: 29199977DOI: 10.1107/S2059798317015418 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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