5VOH
Crystal structure of engineered water-forming NADPH oxidase (TPNOX) bound to NADPH. The G159A, D177A, A178R, M179S, P184R mutant of LbNOX.
Summary for 5VOH
| Entry DOI | 10.2210/pdb5voh/pdb |
| Descriptor | NADH oxidase, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (7 entities in total) |
| Functional Keywords | nadph, redox active cysteine, water-forming oxidase, oxidoreductase |
| Biological source | Lactobacillus brevis KB290 |
| Total number of polymer chains | 4 |
| Total formula weight | 231654.66 |
| Authors | Cracan, V.,Grabarek, Z. (deposition date: 2017-05-02, release date: 2017-08-02, Last modification date: 2023-11-15) |
| Primary citation | Cracan, V.,Titov, D.V.,Shen, H.,Grabarek, Z.,Mootha, V.K. A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells. Nat. Chem. Biol., 13:1088-1095, 2017 Cited by PubMed: 28805804DOI: 10.1038/nchembio.2454 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.302 Å) |
Structure validation
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