5VOH

Crystal structure of engineered water-forming NADPH oxidase (TPNOX) bound to NADPH. The G159A, D177A, A178R, M179S, P184R mutant of LbNOX.

5VOH の概要

• エントリーDOI: 10.2210/pdb5voh/pdb
• 分子名称: NADH oxidase, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (7 entities in total)
• 機能のキーワード: nadph, redox active cysteine, water-forming oxidase, oxidoreductase
• 由来する生物種: Lactobacillus brevis KB290
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 231654.66

構造登録者

Cracan, V.,Grabarek, Z. (登録日: 2017-05-02, 公開日: 2017-08-02, 最終更新日: 2023-11-15)

• 主引用文献: Cracan, V.,Titov, D.V.,Shen, H.,Grabarek, Z.,Mootha, V.K.; A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells.; Nat. Chem. Biol., 13:1088-1095, 2017; PubMed: 28805804; DOI: 10.1038/nchembio.2454

実験手法

X-RAY DIFFRACTION (2.302 Å)