5VO3

Crystal structure of DapE in complex with the products (succinic acid and diaminopimelic acid)

5VO3 の概要

• エントリーDOI: 10.2210/pdb5vo3/pdb
• 分子名称: Succinyl-diaminopimelate desuccinylase, SUCCINIC ACID, 2,6-DIAMINOPIMELIC ACID, ... (5 entities in total)
• 機能のキーワード: dape, hydrolaze, succinic acid, diaminopimelic acid, m28, structural genomics, psi-biology, hydrolase
• 由来する生物種: Haemophilus influenzae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42093.31

構造登録者

Nocek, B. (登録日: 2017-05-01, 公開日: 2018-07-25, 最終更新日: 2023-11-15)

• 主引用文献: Nocek, B.,Reidl, C.,Starus, A.,Heath, T.,Bienvenue, D.,Osipiuk, J.,Jedrzejczak, R.,Joachimiak, A.,Becker, D.P.,Holz, R.C.; Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.; Biochemistry, 57:574-584, 2018; PubMed: 29272107; DOI: 10.1021/acs.biochem.7b01151

実験手法

X-RAY DIFFRACTION (1.954 Å)