5VI7

Crystal structure of the Zika virus NS3 helicase

5VI7 の概要

• エントリーDOI: 10.2210/pdb5vi7/pdb
• 分子名称: helicase, SULFATE ION (3 entities in total)
• 機能のキーワード: helicase, zika virus, viral protein
• 由来する生物種: Zika virus (ZIKV)
• 細胞内の位置: Capsid protein C: Virion . Peptide pr: Secreted . Small envelope protein M: Virion membrane ; Multi-pass membrane protein . Envelope protein E: Virion membrane ; Multi-pass membrane protein . Non-structural protein 1: Secreted . Non-structural protein 2A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Multi-pass membrane protein . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: Q32ZE1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 50366.33

構造登録者

Bukrejewska, M.,Derewenda, U.,Derewenda, Z.S. (登録日: 2017-04-14, 公開日: 2017-09-06, 最終更新日: 2023-10-04)

• 主引用文献: Bukrejewska, M.,Derewenda, U.,Radwanska, M.,Engel, D.A.,Derewenda, Z.S.; Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.; Acta Crystallogr D Struct Biol, 73:767-774, 2017; PubMed: 28876240; DOI: 10.1107/S2059798317010737

実験手法

X-RAY DIFFRACTION (2.005 Å)