5VGP

Fc fragment of human IgG1 antibody, from NIST mAb

5VGP の概要

• エントリーDOI: 10.2210/pdb5vgp/pdb
• 関連するPDBエントリー: 5K8A
• 分子名称: Human Fc fragment with G1F/G0F glycan, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: human, antibody, glycoform, g1f/g0f, immune system
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53347.83

構造登録者

Gallagher, D.T.,Galvin, C.V.,Karageorgos, I.,Marino, J.P. (登録日: 2017-04-11, 公開日: 2018-04-18, 最終更新日: 2023-10-04)

• 主引用文献: Gallagher, D.T.,Galvin, C.V.,Karageorgos, I.; Structure of the Fc fragment of the NIST reference antibody RM8671.; Acta Crystallogr F Struct Biol Commun, 74:524-529, 2018; PubMed: 30198883; DOI: 10.1107/S2053230X18009834

実験手法

X-RAY DIFFRACTION (2.116 Å)