5VF6

Crystal structure of single chain variable fragment (scFv45).

Summary for 5VF6

• Entry DOI: 10.2210/pdb5vf6/pdb
• Descriptor: single chain variable fragment (2 entities in total)
• Functional Keywords: single chain variable fragment, scfv, conformation-sensor antibodies, intrabodies, immune system
• Biological source: Gallus gallus
• Total number of polymer chains: 1
• Total formula weight: 25559.52

Authors

Shrestha, O.K.,Tocilj, A.,Joshua-Tor, L.,Tonks, N.K. (deposition date: 2017-04-06, release date: 2018-01-31, Last modification date: 2023-10-04)

• Primary citation: Krishnan, N.,Bonham, C.A.,Rus, I.A.,Shrestha, O.K.,Gauss, C.M.,Haque, A.,Tocilj, A.,Joshua-Tor, L.,Tonks, N.K.; Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development.; Nat Commun, 9:283-283, 2018; PubMed: 29348454; DOI: 10.1038/s41467-017-02252-2

Experimental method

X-RAY DIFFRACTION (1.635 Å)