5VEN

Murine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5)

Summary for 5VEN

Entry DOI	10.2210/pdb5ven/pdb
Related	5VEM 5VEO
Descriptor	Ectonucleotide pyrophosphatase/phosphodiesterase family member 5, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	hydrolase
Biological source	Mus musculus (Mouse)
Total number of polymer chains	2
Total formula weight	101697.77
Authors	Gorelik, A.,Randriamihaja, A.,Illes, K.,Nagar, B. (deposition date: 2017-04-05, release date: 2017-09-20, Last modification date: 2020-07-29)
Primary citation	Gorelik, A.,Randriamihaja, A.,Illes, K.,Nagar, B. A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5. FEBS J., 284:3718-3726, 2017 Cited by PubMed: 28898552 DOI: 10.1111/febs.14266 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.69 Å)

Structure validation